Sekino has performed as a soloist with the Boston Symphony Orchestra, New World Symphony, Harvard-Radcliffe Orchestra, and Stony Brook Symphony Orchestra. Recital highlights have included the Jordan Hall in Boston, Overtures Series in Washington, D.C., Dame Myra Hess Concerts in Chicago, Hitomi Memorial Hall in Tokyo, Japan, Northeast Asia International Piano Festival in China, and U.S. college campuses such as Eastman School of Music, MIT, and Ithaca College. 

With an extensive repertoire spanning five centuries, Sekino has undertaken various performance projects. Recent projects include performances of Chopin’s complete Op. 10 and Op. 25 Etudes and the Four Ballades, late works by Alexander Scriabin, and world premieres of compositions by David Rakowski and Ross Bauer. In 2023, she undertook a commissioning project with support from the Mu Phi Epsilon Foundation. In this project, composers Mari Kimura and Joseph Di Ponio wrote new works for piano and electronics for Sekino, taking inspiration from the music of Scriabin and Debussy. Committed to the music of our times, Sekino has performed as a soloist in major 20th-century works such as Elliott Carter’s Double Concerto for Harpsichord and Piano, Messiaen’s Oiseaux Exotiques, and Xenakis’ Eonta and Palimpsest at venues including Zankel Hall at Carnegie Hall, Lincoln Theatre in Miami, and Tanglewood Music Center.

Active as an educator, Sekino has given masterclasses at universities and conservatories in the United States and serves as an adjudicator in various competitions. Her prize-winning students regularly participate in festivals and competitions and continue further studies at top schools. During the summers, she has been faculty and guest artist at East Carolina Piano Festival, Atlantic Music Festival, and Northeast Asia International Piano Festival (China). Having previously taught at Colby College, she is currently an Affiliate Artist at Massachusetts Institute of Technology and serves as piano faculty at New England Conservatory Prep School and School of Adult Education.

Also on faculty at MIT; former faculty, Colby College.